I'm fairly opinionated so I may get jumped for my (incorrect) perceptions.
For starters, I like New England a lot. If I could afford to live in a Boston suburb, I would. I'd shovel the snow. But I can't afford it...at least, the last time I checked the prices.
It is colder than the tri-state NY/NJ/CT area and colder than S.E.PA. I think that their (un)employment rates are about the same. I've heard NH has some tax breaks, though the tax picture shouldn't trigger a drastic move, unless it's to retire. Correct: Southern NH is an extension of the Boston metro area and Northern NH is an extension of...Quebec...which could be a good thing.
What I've experienced and had said to me is that New Englanders are more aloof and more reserved than tri-state people. They would consider the direct approach of the tri-state area to be brusque. I kind of like the in-your-face tri-state area approach, since I am familiar with it. When I was visiting my uncle in northern NJ about 10 miles west of the G.W., people would just BS with me and ask me questions wherever I went...amazing for being in the shadow, literally, of the Manhattan skyline. When I was in New England for about a week in 1996 (Concord/Lexington, MA, Danvers, MA and Portland, ME), nobody was like that. It was waaaay more aloof. I liked the whole area, but I know if wouldn't be Jersey. I bet the Philly exurbs are more like Jersey...unless that's what you want to get away from.
Economically, I think it's a wash and shouldn't steer a PA-to-NH move. My .02.